Cureus. 2025 Feb 3;17(2):e78415. doi: 10.7759/cureus.78415. eCollection 2025 Feb.
ABSTRACT
The vanishing or phantom tumor of the lung is an uncommon condition that is caused by an interlobar pleural collection of transudative fluid, resulting from pulmonary congestion. The diagnosis is typically made via chest X-ray, where it appears as a nodular opacity, often mistaken for a pulmonary tumor, hence the term "phantom tumor." This condition is most frequently associated with systemic diseases such as heart failure or chronic kidney disease. The lesion generally resolves with the treatment of hypervolemia with diuretic therapy, though recurrence is possible if the underlying disease becomes decompensated. This report presents two cases of phantom tumors in elderly patients with comorbidities, including heart failure and chronic kidney disease. In both the patients, chest X-rays revealed nodular opacities that resolved after diuretic treatment and fluid management. These cases underscore the importance of early recognition and clinical correlation in distinguishing phantom tumors from true pulmonary nodules, thereby avoiding unnecessary invasive procedures. To sum up, early detection of phantom tumors enables clinicians to refine differential diagnoses and implement timely therapeutic interventions, as these findings are reversible with appropriate management. This report emphasizes the necessity of integrating careful clinical evaluation with imaging techniques to avoid diagnostic errors and excessive treatments. Thus, raising awareness among physicians and radiologists about this rare but significant condition is vital for the effective management of pulmonary congestion.
PMID:40046373 | PMC:PMC11881529 | DOI:10.7759/cureus.78415