Optimizing the Pharmacotherapy of Vascular Surgery Patients at Hospital Admission and Discharge (PHAROS): Protocol for a Quasi-Experimental Clinical Uncontrolled Trial

JMIR Res Protoc. 2025 Mar 19;14:e60728. doi: 10.2196/60728.ABSTRACTBACKGROUND: Patient safety is essential in pharmacotherapy, especially in surgical contexts, due to the elevated risk of drug-related complications. Vascular surgery patients are particularly susceptible because of their complex medi

S Slavka Porubcova

Effect of a Telemedicine Model on Patients With Heart Failure With Reduced Ejection Fraction in a Resource-Limited Setting in Vietnam: Cohort Study

J Med Internet Res. 2025 Mar 19;27:e67228. doi: 10.2196/67228.ABSTRACTBACKGROUND: Heart failure (HF) is a complex, life-threatening condition marked by high morbidity, mortality, reduced functional capacity, poor quality of life, and substantial health care costs. HF with reduced ejection fraction (

H Hoai Thi Thu Nguyen

Identifying Contextual Factors That Shape Cybersecurity Risk Perception for Assisted Living and Health Care Technologies and Wearables: Mixed Methods Study

J Med Internet Res. 2025 Mar 19;27:e64388. doi: 10.2196/64388.ABSTRACTBACKGROUND: Over the last decade, the health care technology landscape has expanded significantly, introducing new and innovative solutions to address health care needs. The implications of cybersecurity incidents in the health ca

A Alvhild Skjelvik

Number of ICD-10 diagnosis fields required to capture sepsis in administrative data and truncation bias: A nationwide prospective registry study

PLoS One. 2025 Mar 19;20(3):e0320054. doi: 10.1371/journal.pone.0320054. eCollection 2025.ABSTRACTBACKGROUND: In observational studies that use administrative data, it is essential to report technical details such as the number of International Classification of Disease (ICD) coding fields extracted

N Nina Vibeche Skei

Diabetes with COVID-19 was a significant risk factor for mortality, mechanical ventilation, and renal replacement therapies: A multicenter retrospective study in Japan

PLoS One. 2025 Mar 19;20(3):e0319801. doi: 10.1371/journal.pone.0319801. eCollection 2025.ABSTRACTWe conducted a multicenter retrospective cohort study across 38 hospitals in Chiba, Japan, between February 1, 2020 and November 31, 2021 to investigate the effect of coronavirus disease 2019 (COVID-19)

H Hirotsugu Suwanai

How do people feel about sleep diaries? Factors influencing sleep diaries completion with and without daily exposure to light

PLoS One. 2025 Mar 19;20(3):e0317788. doi: 10.1371/journal.pone.0317788. eCollection 2025.ABSTRACTSTUDY OBJECTIVES: Sleep diary is a common tool in sleep medicine, but was barely validated in practice so far. Lack of light exposure is associated with sleep disorders, especially insomnia. For that pu

B Boris Gass

Remedial colon hydrotherapy device enema as a salvage strategy for inadequate bowel preparation for colonoscopy: A retrospective cohort study

PLoS One. 2025 Mar 19;20(3):e0319493. doi: 10.1371/journal.pone.0319493. eCollection 2025.ABSTRACTOBJECTIVE: Colon hydrotherapy devices serve as a physiotherapeutic modality to manage colonic disorders by promoting intestinal peristalsis and enhancing gastrointestinal functionality. This study aims

D Dongxuan Zhang

Emergency admission, previous delirium tremens and increased liver stiffness as risk factors for severe alcohol withdrawal - A prospective study

PLoS One. 2025 Mar 19;20(3):e0320083. doi: 10.1371/journal.pone.0320083. eCollection 2025.ABSTRACTOBJECTIVE: To determine if increased liver stiffness (ILS) is a risk factor for patients with alcohol withdrawal to develop severe alcohol withdrawal symptoms (SAWS) like delirium tremens (DT) or withdr

T Tobias Zellner

Development and evaluation of a Physiotherapy-led, WHO-ICOPE-Based, Person-Centered Integrated Care Program (PTICOPE) module to enhance intrinsic capacity in older adults: Protocol for a randomized controlled trial

PLoS One. 2025 Mar 19;20(3):e0318513. doi: 10.1371/journal.pone.0318513. eCollection 2025.ABSTRACTBACKGROUND: Declining intrinsic capacity (IC), encompassing domains such as locomotion, cognitive function, vitality, vision, hearing, and psychological well-being, is prevalent among older adults, impa

N Nurhazrina Noordin

Bilateral Knee Synovial Chondromatosis in a 2-Year-Old Girl: First Reported Case and Literature Review

Am J Case Rep. 2025 Mar 19;26:e945921. doi: 10.12659/AJCR.945921.ABSTRACTBACKGROUND Synovial chondromatosis (SC) is a rare monoarticular benign condition characterized by the development of intra- or periarticular cartilage-like nodules or loose bodies. Typically affecting middle-aged men, SC is exc

A Ana Paula Fernandes Barbosa

Predicting Readmission Among High-Risk Discharged Patients Using a Machine Learning Model With Nursing Data: Retrospective Study

JMIR Med Inform. 2025 Mar 5;13:e56671. doi: 10.2196/56671.ABSTRACTBACKGROUND: Unplanned readmissions increase unnecessary health care costs and reduce the quality of care. It is essential to plan the discharge care from the beginning of hospitalization to reduce the risk of readmission. Machine lear

E Eui Geum Oh

Assessing brain vascular impairment, white matter lesions and ApoE status as predictors of behavioral and psychological symptoms of dementia (BPSD) in a multicentre sample of patients with Alzheimer's disease: a multidisciplinary retrospective study

Ann Ist Super Sanita. 2025 Jan-Mar;61(1):42-49. doi: 10.4415/ANN_25_01_06.ABSTRACTBACKGROUND: Understanding pathogenetic background and risk factors is the primary step to a better behavioral and psychological symptoms of dementia (BPSD) management. To this aim, this exploratory study is designed to

L Luana Vaianella

Patient and Provider Perspectives of a Web-Based Intervention to Support Symptom Management After Radioactive Iodine Treatment for Differentiated Thyroid Cancer: Qualitative Study

JMIR Form Res. 2025 Mar 19;9:e60588. doi: 10.2196/60588.ABSTRACTBACKGROUND: Patients diagnosed with differentiated thyroid cancer (DTC) who receive radioactive iodine (RAI) treatment experience acute, medium, and late treatment effects. The timing and severity of these effects vary by individual; co

A Alaina L Carr

Digital Health Literacy and Attitudes Toward eHealth Technologies Among Patients With Cardiovascular Disease and Their Implications for Secondary Prevention: Survey Study

JMIR Form Res. 2025 Mar 19;9:e63057. doi: 10.2196/63057.ABSTRACTBACKGROUND: Cardiovascular disease is the major cause of death worldwide, leading to a significant socioeconomic burden. Although secondary prevention is a cornerstone in chronic disease management, adherence to guideline recommendation

G Greta Ullrich

Differences in the clinical presentation of acute 3,4-methylenedioxymetamfetamine intoxication by co-intoxication and patient sex to European emergency departments

Clin Toxicol (Phila). 2025 Mar;63(3):183-192. doi: 10.1080/15563650.2025.2453052. Epub 2025 Mar 19.ABSTRACTINTRODUCTION: This study hypothesized that 3,4-methylenedioxymetamfetamine intoxication presents with distinct clinical features and outcomes when combined with other substances of misuse, comp

J Joep J J Ouwerkerk

Safety profile of antivenom in a cohort of patients envenomed by Deinagkistrodon acutus in Hangzhou, Zhejiang Province, Southeast China

Clin Toxicol (Phila). 2025 Mar;63(3):196-203. doi: 10.1080/15563650.2025.2449938. Epub 2025 Mar 19.ABSTRACTINTRODUCTION: Antivenom treatment is the specific treatment for Deinagkistrodon acutus envenomation. However, safety concerns regarding the use of antivenom in this population have been reporte

M Mengyun Tu

An Up-to-Date Description of the Use of Non-steroidal Anti-inflammatory Drugs (NSAIDs) in Italy: Evidence from Real Clinical Practice

Adv Ther. 2025 Mar 19. doi: 10.1007/s12325-025-03153-3. Online ahead of print.ABSTRACTINTRODUCTION: The prescription of non-steroidal anti-inflammatory drugs (NSAIDs) covered by the Italian National Health Service is limited to certain pathologies defined in the 2018 update of Note 66 of the Italian

V Valentina Perrone

A Real-World Study on the Use, Effectiveness, and Safety of Esketamine Nasal Spray in Patients with Treatment-Resistant Depression: INTEGRATE Study

Adv Ther. 2025 Mar 19. doi: 10.1007/s12325-025-03149-z. Online ahead of print.ABSTRACTINTRODUCTION: The INTEGRATE study aimed to provide information on the use, effectiveness, and safety of esketamine nasal spray (ESK-NS) for the treatment of treatment-resistant depression (TRD) in real-world practi

P Patricio Molero

Proteomic Profiling and Therapeutic Targeting of Oxidative Stress in Autoimmune Encephalitis

J Mol Neurosci. 2025 Mar 19;75(2):38. doi: 10.1007/s12031-025-02332-9.ABSTRACTAutoimmune encephalitis (AE) is an immune-mediated non-infectious disease, and novel and robust biomarkers are needed to improve the diagnosis and prognostic outcomes of AE. Oxidative stress is a ubiquitous cellular proces

F Fan Zhang

Microneedling with autologous platelet rich fibrin versus microneedling with autologous platelet rich plasma in treatment of abdominal stretch marks: a randomized comparative study

Arch Dermatol Res. 2025 Mar 19;317(1):602. doi: 10.1007/s00403-025-04135-9.ABSTRACTStriae distensae (SD), commonly known as stretch marks, are a common dermatological condition with challenging therapeutic interventions and varying outcomes. The current study aims to compare the clinical response, e

A Asmaa Ehab Mohamed Ahmed

Connectivity related to major brain functions in Alzheimer disease progression: microstructural properties of the cingulum bundle and its subdivision using diffusion-weighted MRI

Eur Radiol Exp. 2025 Mar 19;9(1):32. doi: 10.1186/s41747-025-00570-5.ABSTRACTBACKGROUND: The cingulum bundle is a brain white matter fasciculus associated with the cingulate gyrus. It connects areas from the temporal to the frontal lobe. It is composed of fibers with different terminations, lengths,

M Mattia Ricchi

Application of the anti-IgLON5 disease composite score to assess severity, clinical course, and mortality in a French cohort

J Neurol. 2025 Mar 19;272(4):273. doi: 10.1007/s00415-025-13001-7.ABSTRACTAnti-IgLON5 disease presents with diverse symptoms, whose severity can be measured by the anti-IgLON5 disease composite score (ICS). This study applied the ICS to a retrospective anti-IgLON5 disease cohort (n = 52; median age

A Antonio Farina

Comparative analysis of the lumboperitoneal shunt versus ventriculoperitoneal shunt for leptomeningeal metastasis-associated hydrocephalus in non-small cell lung cancer

Acta Neurochir (Wien). 2025 Mar 19;167(1):81. doi: 10.1007/s00701-025-06490-y.ABSTRACTPURPOSE: Leptomeningeal metastasis (LM)-associated hydrocephalus is a rare but severe complication of non-small cell lung cancer (NSCLC). The spread of malignant cells to the leptomeninges obstructs cerebrospinal f

M Minjoon Kim

Exploring the role of surgical margins and reoperation in basal cell carcinoma recurrence: a study of 3036 cases

Arch Dermatol Res. 2025 Mar 19;317(1):604. doi: 10.1007/s00403-025-04084-3.ABSTRACTINTRODUCTION: Basal cell carcinoma (BCC) is the most common type of skin cancer globally, with its prevalence increasing due to chronic ultraviolet (UV) radiation exposure. Although surgical excision remains the corne

M Martin Iurilli