J Eval Clin Pract. 2025 Mar;31(2):e70052. doi: 10.1111/jep.70052.ABSTRACTOBJECTIVES: Fatigue is a common symptom in patients with the chronic obstructive pulmonary disease (COPD). The aim of this study was to assess patient-reported fatigue in the COPD and to investigate their attempts to cope with
J Clin Gastroenterol. 2025 Mar 17. doi: 10.1097/MCG.0000000000002142. Online ahead of print.ABSTRACTThis paper assesses the existing literature to explore the association between obstructive sleep apnea (OSA) and cirrhosis. While OSA's impact on metabolic dysfunction-associated steatotic liver disea
J Crohns Colitis. 2025 Mar 19:jjaf047. doi: 10.1093/ecco-jcc/jjaf047. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Extracellular RNAs (exRNAs) including in serum, show potential as non-invasive biomarkers. However, their (patho)physiological role is still not fully understood. In this study, w
Endocrinology. 2025 Mar 19:bqaf055. doi: 10.1210/endocr/bqaf055. Online ahead of print.ABSTRACTDiabetes is the most expensive chronic disease in the U.S. with over $400 billion in annual costs and it affects over 38 million Americans. While major advances in drug treatment have been made for type 2
Epidemiol Serv Saude. 2025 Mar 14;34:e20240256. doi: 10.1590/S2237-96222025v34e20240256.en. eCollection 2025.ABSTRACTOBJECTIVE: To describe an interconsultation project with specialists and family health teams participating in a telemedicine project in the state of Rio Grande do Norte, Brazil.METHOD
Immun Inflamm Dis. 2025 Mar;13(3):e70179. doi: 10.1002/iid3.70179.ABSTRACTOBJECTIVES: The objective of this study is to analyze and summarize the clinical characteristics and prognosis of lupus nephritis (LN) patients with thrombocytopenia and to improve the cognition of the disease.METHODS: 896 LN
Rev Assoc Med Bras (1992). 2025 Mar 17;71(1):e20240902. doi: 10.1590/1806-9282.20240902. eCollection 2025.ABSTRACTOBJECTIVE: The objective of this study was to compare the long-term efficacy of spinal fusion surgery versus non-surgical treatment for chronic radicular lumbar spondylopathy.METHODS: A
Int J Surg Pathol. 2025 Mar 19:10668969251323932. doi: 10.1177/10668969251323932. Online ahead of print.ABSTRACTIntroductionPancreaticoduodenectomy is the standard treatment for resectable pancreatic head malignancies and other ampullary/peri-ampullary lesions. It is also the standard of care for sy
Pediatr Pulmonol. 2025 Mar;60(3):e71028. doi: 10.1002/ppul.71028.ABSTRACTINTRODUCTION: Pediatric pulmonary hypertension (PH) significantly contributes to morbidity and mortality due to the progressive nature of the disease in some subtypes, which leads to severe right heart failure, impaired oxygena
J Rehabil Med. 2025 Mar 19;57:jrm42577. doi: 10.2340/jrm.v57.42577.ABSTRACTOBJECTIVE: To explore perceived barriers to and facilitators of behaviour change towards a more active lifestyle in people with neuromuscular diseases.DESIGN: A qualitative study.SUBJECTS: Nineteen subjects (63% females, age
Liver Int. 2025 Apr;45(4):e70062. doi: 10.1111/liv.70062.ABSTRACTAIM: Cirrhotic cardiomyopathy is characterised by myocardial dysfunction in patients with cirrhosis in the absence of other cardiac conditions. We aimed to develop and validate a scoring system to identify patients at high risk for red
ObjectivesThis study aims to compare Chitogel^(®) with topical corticosteroid versus PureRegen^(®) gel on wound healing and postoperative outcomes in the treatment of chronic rhinosinusitis.MethodsA double-blinded randomized controlled trial was performed with patients undergoing functional endoscop
Liver Int. 2025 Apr;45(4):e16241. doi: 10.1111/liv.16241.ABSTRACTBACKGROUND AND AIMS: The Baveno VII consensus recommends spleen stiffness measurement (SSM) for the detection of clinically significant portal hypertension (CSPH) in patients with compensated advanced chronic liver disease (cACLD). We
J Clin Lab Anal. 2025 Mar 19:e70009. doi: 10.1002/jcla.70009. Online ahead of print.ABSTRACTBACKGROUND: Johne's disease, also known as paratuberculosis, is a chronic granulomatous enteritis disease that affects ruminants worldwide.OBJECTIVE: The objective of this study was to assess the effectivenes
Technol Health Care. 2025 Mar;33(2):1081-1087. doi: 10.1177/09287329241295867. Epub 2024 Dec 1.ABSTRACTBackgroundTerminal ileitis (TI) is an inflammatory condition of the distal portion of the ileum.ObjectiveTo investigate the changes and significance of neurotensin (NT) in the course of experimenta
Technol Health Care. 2025 Mar;33(2):951-958. doi: 10.1177/09287329241291370. Epub 2024 Nov 25.ABSTRACTBackgroundChronic Kidney Disease (CKD) is a significant public health issue, affecting 37 million people in the United States. CKD often leads to malnutrition, particularly in advanced stages, contr
Technol Health Care. 2025 Mar;33(2):959-973. doi: 10.1177/09287329241291430. Epub 2024 Nov 25.ABSTRACTBackgroundHepatocellular carcinoma (HCC) is a primary cancer, accounting for 90% of primary liver cancer, mainly occurring in patients with cirrhosis and chronic liver disease.ObjectiveTo investigat
FASEB J. 2025 Mar 31;39(6):e70461. doi: 10.1096/fj.202401445R.ABSTRACTMoyamoya disease (MMD) is a chronic occlusive cerebrovascular ailment with a progressively rising incidence, yet its precise etiology and pathogenesis remain elusive. Adult MMD-related datasets GSE189993 and GSE157628 were procure
Fam Pract. 2025 Feb 7;42(2):cmaf010. doi: 10.1093/fampra/cmaf010.ABSTRACTBACKGROUND/OBJECTIVE: the determination of the carotid total plaque area (TPA) is an indicator of subclinical atherosclerosis and a useful tool in early cardiovascular prevention. Classically, diabetes has been considered the m
J Med Virol. 2025 Mar;97(3):e70302. doi: 10.1002/jmv.70302.ABSTRACTChronic hepatitis B (CHB) infection represents a significant global public health issue, often leading to hepatitis B virus (HBV)-related liver cirrhosis (HBV-LC) with poor prognoses. Early identification of HBV-LC risk is essential
Zhongguo Dang Dai Er Ke Za Zhi. 2025 Mar 15;27(3):334-339. doi: 10.7499/j.issn.1008-8830.2409125.ABSTRACTOBJECTIVES: To analyze the clinical characteristics of diffuse panbronchiolitis (DPB) in children and to enhance the clinical diagnosis and treatment of this disease.METHODS: A retrospective anal
Biosci Rep. 2025 Mar 19:BSR20241663. doi: 10.1042/BSR20241663. Online ahead of print.ABSTRACTThe allostatic load (AL) concept measures physiological dysregulation in response to internal and external stressors that accumulate across the life course. AL has been consistently linked to chronic disease
J Vet Intern Med. 2025 Mar-Apr;39(2):e70052. doi: 10.1111/jvim.70052.ABSTRACTBACKGROUND: Urine protein-creatinine ratio (UPC) and urine specific gravity (USG) are important measurements in the determination of renal proteinuria and chronic kidney disease. Biological and analytical variation estimate
Ann Med. 2025 Dec;57(1):2477294. doi: 10.1080/07853890.2025.2477294. Epub 2025 Mar 19.ABSTRACTBACKGROUND: Chronic hepatitis B (CHB) is a common cause of liver cirrhosis (LC), a condition associated with an unfavourable prognosis. Therefore, timely diagnosis of LC in CHB patients is crucial.OBJECTIVE
