Epidemiological analysis of intra-abdominal infections in Italy from the Italian register of complicated intra-abdominal infections-the IRIS study: a prospective observational nationwide study

World J Emerg Surg. 2025 Mar 17;20(1):22. doi: 10.1186/s13017-025-00590-x.ABSTRACTBACKGROUND: Intra-abdominal infections (IAIs) are common and severe surgical emergencies associated with high morbidity and mortality. In recent years, there has been a worldwide increase in antimicrobial resistance as

F Federico Coccolini

Bacteraemia in a Nigerian hospital: Implementing antimicrobial resistance surveillance

J Public Health Afr. 2025 Feb 7;16(1):655. doi: 10.4102/jphia.v16i1.655. eCollection 2025.ABSTRACTBACKGROUND: Surveillance of drug-resistant infections is crucial for antimicrobial resistance (AMR) control. Implementing surveillance in low- and middle-income countries (LMICs) is challenging.AIM: To

A Adewale A Amupitan

Central line-associated bloodstream infections (CLABSI) in pediatric and neonatal intensive care units-The VINCat program 2013-2022

Enferm Infecc Microbiol Clin (Engl Ed). 2025 Mar 12:S2529-993X(25)00058-9. doi: 10.1016/j.eimce.2024.09.014. Online ahead of print.ABSTRACTINTRODUCTION: Central line-associated bloodstream infections (CLABSI) are among the most common and preventable hospital-acquired infections in pediatric and neo

M Mireia Urrea Ayala

Pediatric Gram-negative bloodstream infections: epidemiology, antibiotic resistance, clinical outcomes and factors affecting mortality, a single center retrospective study

J Infect Dev Ctries. 2025 Feb 28;19(2):238-247. doi: 10.3855/jidc.20258.ABSTRACTINTRODUCTION: The increasing prevalence of Gram-negative bloodstream infections in pediatric patients poses significant treatment challenges, particularly from multi-drug resistant (MDR) strains. Despite advances in medi

S Seyhan Yilmaz

Adherence to standard infection prevention and control practices and factors associated among healthcare workers at Juba Teaching Hospital, Juba-South Sudan: a cross-sectional study

J Health Popul Nutr. 2025 Mar 6;44(1):66. doi: 10.1186/s41043-025-00807-4.ABSTRACTBACKGROUND: Hospital-acquired infections, including COVID-19 and sepsis, pose a significant threat to healthcare workers' productivity and patients' safety globally. Adhering to standard infection prevention and contro

C Chubang Augustine Khamsa

Neon Pink Breast Milk Stain in the NICU

Cureus. 2025 Feb 3;17(2):e78425. doi: 10.7759/cureus.78425. eCollection 2025 Feb.ABSTRACTPink discoloration in breast milk is a rare phenomenon arising from various benign or pathological causes. Serratia marcescens, a gram-negative bacterium known for its characteristic red pigment prodigiosin, is

B Brenda Stanley

Current trends in the epidemiology of multidrug-resistant and beta-lactamase-producing Pseudomonas aeruginosa in Asia and Africa: a systematic review and meta-analysis

PeerJ. 2025 Feb 24;13:e18986. doi: 10.7717/peerj.18986. eCollection 2025.ABSTRACTPseudomonas aeruginosa continues to be a significant contributor to high morbidity and mortality rates worldwide, particularly due to its role in severe infections such as hospital-acquired conditions, including ventila

M Mohd Zulkifli Salleh

Utilising routinely collected clinical data through time series deep learning to improve identification of bacterial bloodstream infections: a retrospective cohort study

Lancet Digit Health. 2025 Mar;7(3):e205-e215. doi: 10.1016/j.landig.2025.01.010.ABSTRACTBACKGROUND: Blood cultures are the gold standard for diagnosing bacterial bloodstream infections, but test results are only available 24-48 h after sampling. We aimed to develop and evaluate models using health-c

D Damien K Ming

"Unmasking the Uncommon": A case series of multi-drug resistant Elizabethkingia meningoseptica causing late-onset sepsis and meningitis in preterm neonates

F1000Res. 2025 Feb 6;13:1367. doi: 10.12688/f1000research.158137.2. eCollection 2024.ABSTRACTElizabethkingia meningoseptica is an uncommon nosocomial pathogen that causes meningitis, pneumonia, and sepsis in neonates and in immunocompromised individuals. It exhibits resistance to many commonly emplo

P Prajnha U P

Identification of circulating Tfh/Th subsets as a biomarker of developed hospital-acquired pneumonia

Front Immunol. 2025 Jan 22;16:1513939. doi: 10.3389/fimmu.2025.1513939. eCollection 2025.ABSTRACTBACKGROUND: This study aimed to explore the possible value of follicular helper T (Tfh) cells in hospital-acquired pneumonia (HAP).METHODS: Flow cytometry was used to measure circulating Tfh and helper T

Y Yuan Peng

A randomized, double-blind, placebo controlled trial of IL-7 in critically ill COVID-19 patients

JCI Insight. 2025 Feb 4:e189150. doi: 10.1172/jci.insight.189150. Online ahead of print.ABSTRACTBACKGROUND: Lymphopenia and failure of lymphocytes to mount an early IFN-γ response correlate with increased mortality in COVID-19. Given the essential role of CD4 helper and CD8 cytotoxic cells in elimin

M Manu Shankar-Hari

The effect of GM-CSF and predictors of treatment outcome in pediatric septic shock patients

Ital J Pediatr. 2025 Feb 4;51(1):25. doi: 10.1186/s13052-025-01863-6.ABSTRACTBACKGROUND: Pediatric septic shock is a critical condition associated with high mortality rates, largely due to sepsis-induced immunosuppression. Granulocyte-macrophage colony-stimulating factor (GM-CSF) has been explored a

Z Zhen-Hao Yu

An integrative review on the risk factors, prevention, and control strategies for carbapenem-resistant Acinetobacter baumannii colonization in critically ill patients

Front Microbiol. 2025 Jan 10;15:1519906. doi: 10.3389/fmicb.2024.1519906. eCollection 2024.ABSTRACTThe presence of carbapenem-resistant Acinetobacter baumannii (CRAb) has become one of the leading causes of life-threatening, hospital-acquired infections globally, especially with a notable prevalence

S Shihan Zhang

Unveiling results and insights from multinational, multicenter Study of Prescribing patterns and Effectiveness of Ceftolozane/Tazobactam Real-world Analysis (SPECTRA)

J Glob Antimicrob Resist. 2025 Mar;41:272-279. doi: 10.1016/j.jgar.2025.01.007. Epub 2025 Jan 27.ABSTRACTOBJECTIVES: Antibacterial-resistant gram-negative hospital-acquired infections result in significant morbidity and mortality. In clinical trials, ceftolozane/tazobactam (C/T) has been effective a

A Alex Soriano

Comparative Analysis of Clinical Characteristics and Antimicrobial Resistance Between Acinetobacter baumannii and Other Acinetobacter Species

Pathogens. 2025 Jan 8;14(1):46. doi: 10.3390/pathogens14010046.ABSTRACTAcinetobacter species are major pathogens responsible for hospital-acquired infections. This study aimed to compare the clinical characteristics, outcomes, and antimicrobial resistance between Acinetobacter baumannii (AB) and non

S Si-Ho Kim

Prevalence and mortality associated with multidrug-resistant infections in adult intensive care units in Argentina (PREV-AR)

Antimicrob Agents Chemother. 2025 Mar 5;69(3):e0142624. doi: 10.1128/aac.01426-24. Epub 2025 Jan 22.ABSTRACTData from low and middle-income countries (LMICs) on multidrug-resistant microorganisms (MDROs) in intensive care units (ICUs) are scarce. Working in several ICUs in Argentina, we sought to es

W Wanda Cornistein

Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama

Rev Panam Salud Publica. 2025 Jan 20;49:e7. doi: 10.26633/RPSP.2025.7. eCollection 2025.ABSTRACTOBJECTIVE: To conduct a point prevalence survey (PPS) of antibiotic use in the main pediatric tertiary-level hospital in Panama City to establish antibiotic prevalence and identify key areas for addressin

X Ximena Norero

From Isolation to Application: Utilising Phage-Antibiotic Synergy in Murine Bacteremia Model to Combat Multidrug-Resistant Enterococcus faecalis

Microb Biotechnol. 2025 Jan;18(1):e70075. doi: 10.1111/1751-7915.70075.ABSTRACTEnterococcus species, natural inhabitants of the human gut, have become major causes of life-threatening bloodstream infections (BSIs) and the third most frequent cause of hospital-acquired bacteremia. The rise of high-le

F Fatma Al-Zahraa A Yehia

Clinical and genomic characterization of Klebsiella pneumoniae infections in Dhaka, Bangladesh

J Glob Antimicrob Resist. 2025 Mar;41:52-58. doi: 10.1016/j.jgar.2024.12.016. Epub 2024 Dec 24.ABSTRACTBACKGROUND: Klebsiella pneumoniae (Kpn), a WHO priority pathogen with high rates of antimicrobial resistance (AMR), has emerged as a leading cause of hospital acquired pneumonia and neonatal sepsis

Z Zannat Kawser

A Three-Year Analysis of Mortality in Clostridioides difficile Patients in a Tertiary Center

Cureus. 2024 Nov 23;16(11):e74291. doi: 10.7759/cureus.74291. eCollection 2024 Nov.ABSTRACTBACKGROUND/OBJECTIVES: Clostridioides difficile, an anaerobic bacillus ubiquitous in nature, is the leading cause of hospital-acquired diarrhoea and one of the main causes of mortality by nosocomial infections

G George S Gherlan

Peripheral Blood Levels of IL-27, IFABP, and DAO at Early Onset as Predictors of 28-Day Mortality in Enterogenic Sepsis Patients: A Single-Center, Prospective Pilot Study

Infect Drug Resist. 2024 Dec 7;17:5439-5449. doi: 10.2147/IDR.S496918. eCollection 2024.ABSTRACTBACKGROUND: Currently, there is a lack of serum biomarkers that can accurately predict the short-term prognosis of enterogenic sepsis.METHODS: 99 patients with enterogenic sepsis were categorized based on

Y Yin Ni

A multidisciplinary comprehensive nursing Management Approach for Catheter-related bloodstream infections

Eur J Clin Microbiol Infect Dis. 2025 Feb;44(2):365-373. doi: 10.1007/s10096-024-05002-7. Epub 2024 Dec 10.ABSTRACTBACKGROUND: Catheter-related bloodstream infection (CR-BSI) stands as one of the leading causes of hospital-acquired infections, often resulting in high healthcare expenditure and morta

L Lingli Xu

Bloodstream infections caused by Staphylococcus aureus in patients admitted to King Abdulaziz University Hospital, Jeddah, Saudi Arabia

Eur Rev Med Pharmacol Sci. 2024 Nov;28(22):4621-4633. doi: 10.26355/eurrev_202411_36956.ABSTRACTOBJECTIVE: Currently, there is a limited amount of published data on the incidence of bloodstream infections (BSI) caused by both methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-suscept

A A Albuhairy

Cefiderocol in the Successful Treatment of Complicated Hospital-Acquired K. pneumoniae NDM, OXA48 Intraabdominal Infection

Infect Drug Resist. 2024 Nov 23;17:5163-5170. doi: 10.2147/IDR.S485450. eCollection 2024.ABSTRACTBACKGROUND: Klebsiella pneumoniae MDR/XDR constitutes a difficult to treat bacteria in a number of infections as there are few therapeutic options. Promising drugs in such cases can be cefiderocol, aztre

I Ignacy Tarski